RESUMO
Allele frequencies for the seven PCR-based loci (LDLR, GYPA, HBGG, D7S8, Gc, HLA-DQAI, and D1S80) were determined in a Black African population from Zimbabwe. All loci are highly polymorphic and meet Hardy-Weinberg expectations. An interclass correlation analysis detected only two significant departures from independence out of 21 pair-wise comparisons of the 7 loci. The Black African allele frequency data are similar to African American data at four of the seven PCR-based loci.
Assuntos
População Negra/genética , Frequência do Gene , Genética Populacional , Antígenos HLA-DQ/genética , DNA/genética , Marcadores Genéticos , Cadeias alfa de HLA-DQ , Humanos , Reação em Cadeia da Polimerase , ZimbábueRESUMO
Allele frequencies for six tetrameric short tandem repeat (STR) loci CSF1PO, TPOX, THO1, D3S1358, VWA, and FGA were determined in a Black African sample population from Zimbabwe. All loci are highly polymorphic and meet Hardy-Weinberg expectations. An inter-class correlation test analysis detected only one departure from independence out of 15 pair-wise comparisons of the six loci (i.e., CSF1PO/VWA loci, P = 0.026). The allele frequency data at four of the six STR loci in the Black African sample population are similar to African American data.
